Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 15/20 | 0.59 |
| ▸ | DRD2 | P14416 | 14/20 | 0.59 |
| ▸ | HTR1A | P08908 | 13/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21661933 | 0.83 | DRD2 (0.59) | DRD4DRD2HTR1AKCNH2MAP4K4 | |
| SCHEMBL26141032 | 0.83 | HTR4 (0.45) | DRD4DRD2HTR1AKCNH2HRH1 | |
| Hydrochloric Acid SCHEMBL21642940 | 0.82 | DRD2 (0.58) | DRD4DRD2HTR1AKCNH2MAP4K4 | |
| SCHEMBL21699883 | 0.81 | DRD2 (0.67) | DRD4DRD2HTR1AKCNH2TLR9 | |
| SCHEMBL17888476 | 0.79 | DRD2 (0.53) | DRD4DRD2HTR1AKCNH2MAP4K4 | |
| SCHEMBL21699882 | 0.76 | DRD2 (0.65) | DRD4DRD2HTR1AKCNH2 | |
| SCHEMBL13490648 | 0.76 | DRD2 (0.60) | DRD4DRD2HTR1AKCNH2 | |
| SCHEMBL1610517 | 0.75 | CCR1 (0.52) | DRD4DRD2HTR1AKCNH2MAP4K4 | |
| SCHEMBL28229736 | 0.74 | MAPK11 (0.45) | DRD4DRD2HRH1TLR9TLR8 | |
| SCHEMBL14240402 | 0.74 | MAP4K4 (0.51) | DRD4DRD2HTR1AKCNH2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155320-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |