SCHEMBL2169993

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16496417	1.00	POLB (0.48)	POLBMAPTNPSR1HTTALDH1A1
	SCHEMBL16496563	0.90	THRB (0.38)	POLBMAPTNPSR1LMNAMEN1
	SCHEMBL2169679	0.90	THRB (0.38)	POLBMAPTNPSR1LMNAMEN1
	SCHEMBL2170699	0.83	TNFRSF1A (0.40)	POLBMAPTHTTALDH1A1LMNA
	SCHEMBL2170701	0.83	TNFRSF1A (0.40)	POLBMAPTHTTALDH1A1LMNA
	SCHEMBL16496217	0.82	THRB (0.46)	MAPTLMNATNFRSF1A
	SCHEMBL2170309	0.82	THRB (0.46)	MAPTLMNATNFRSF1A
	SCHEMBL16495901	0.81	TNFRSF1A (0.39)	POLBMAPTHTTALDH1A1LMNA
	SCHEMBL16496483	0.81	THRB (0.37)	LMNAKMT2AKDM4EHPGD
	SCHEMBL2169568	0.81	THRB (0.37)	LMNAKMT2AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.