Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170701 | 1.00 | TNFRSF1A (0.40) | TNFRSF1AMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL2169802 | 0.90 | LMNA (0.41) | TNFRSF1AMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL16495653 | 0.90 | LMNA (0.41) | TNFRSF1AMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL2170309 | 0.89 | THRB (0.46) | TNFRSF1AMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL16496217 | 0.89 | THRB (0.46) | TNFRSF1AMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL2169404 | 0.88 | MAPK1 (0.41) | TNFRSF1AMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL2169973 | 0.88 | MAPK1 (0.41) | TNFRSF1AMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL2170982 | 0.88 | TNFRSF1A (0.41) | TNFRSF1AMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL2169175 | 0.88 | TNFRSF1A (0.39) | TNFRSF1AMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL2169177 | 0.88 | TNFRSF1A (0.39) | TNFRSF1AMAPK1HSD17B10LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110301200-A1 | THYROID RECEPTOR LIGANDS | CADILA HEALTHCARE LIMITED (IN) | 2011-12-08 | — | — | US | claimed |
| EP-2346814-A2 | THYROID RECEPTOR LIGANDS | Cadila Healthcare Limited (IN) | 2011-07-27 | — | — | EP | claimed |
| WO-2010049946-A2 | THYROID RECEPTOR LIGANDS | CADILA HEALTHCARE LIMITED (IN) | 2010-05-06 | — | — | WO | claimed |
| US-20110301200-A1 | THYROID RECEPTOR LIGANDS | CADILA HEALTHCARE LIMITED (IN) | 2011-12-08 | — | — | US | disclosed |
| EP-2346814-A2 | THYROID RECEPTOR LIGANDS | Cadila Healthcare Limited (IN) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010049946-A2 | THYROID RECEPTOR LIGANDS | CADILA HEALTHCARE LIMITED (IN) | 2010-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301200-A1 | THYROID RECEPTOR LIGANDS | TSHR, THRB, THRA | TNFRSF1A 401/4885MAPK1 2130/4885HSD17B10 911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.