Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31443298 | 0.81 | LMNA (0.45) | BAZ2BBAZ2AKMT2AGAAMAPT | |
| SCHEMBL21700027 | 0.77 | MAPT (0.40) | BAZ2BBAZ2AKMT2AGAAMAPT | |
| SCHEMBL17838285 | 0.77 | BAZ2B (0.43) | BAZ2BBAZ2AKMT2AGAAMAPT | |
| SCHEMBL21699991 | 0.77 | KMT2A (0.39) | BAZ2BBAZ2AKMT2AGAAMAPT | |
| SCHEMBL17838308 | 0.77 | BAZ2B (0.43) | BAZ2BBAZ2AKMT2AGAAMAPT | |
| SCHEMBL17700812 | 0.77 | KMT2A (0.39) | BAZ2BBAZ2AKMT2AGAAMAPT | |
| SCHEMBL21699997 | 0.76 | CA1 (0.47) | BAZ2BBAZ2AKMT2AGAAMAPT | |
| SCHEMBL16236608 | 0.76 | BAZ2B (0.40) | BAZ2BBAZ2AKMT2AGAAMAPT | |
| SCHEMBL31443391 | 0.76 | KMT2A (0.43) | KMT2AGAAMAPTALDH1A1LMNA | |
| SCHEMBL21699994 | 0.75 | KMT2A (0.37) | BAZ2BBAZ2AKMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608326-A1 | TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS | IRBM S.P.A. (IT) | 2020-02-12 | — | — | EP | disclosed |