Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22221803 | 0.83 | BAZ2B (0.42) | KMT2AMAPTBAZ2BBAZ2AALDH1A1 | |
| SCHEMBL21699991 | 0.83 | KMT2A (0.39) | KMT2AMAPTMEN1CASP3TRPV1 | |
| SCHEMBL23762448 | 0.79 | KMT2A (0.33) | KMT2AMAPTMEN1CASP3TRPV1 | |
| SCHEMBL21700069 | 0.77 | ALDH1A1 (0.31) | KMT2AMEN1ALDH1A1STAT3SMN1; SMN2 | |
| SCHEMBL23762691 | 0.77 | OPRM1 (0.39) | KMT2AMEN1 | |
| SCHEMBL31443298 | 0.75 | LMNA (0.45) | KMT2AMAPTBAZ2BBAZ2AALDH1A1 | |
| SCHEMBL21699985 | 0.75 | BAZ2B (0.43) | KMT2AMAPTMEN1CASP3TRPV1 | |
| SCHEMBL21699971 | 0.74 | JAK2 (0.33) | ALDH1A1GAASMN1; SMN2THRB | |
| SCHEMBL21700027 | 0.71 | MAPT (0.40) | KMT2AMAPTBAZ2BBAZ2AALDH1A1 | |
| SCHEMBL17838285 | 0.71 | BAZ2B (0.43) | KMT2AMAPTBAZ2BBAZ2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608326-A1 | TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS | IRBM S.P.A. (IT) | 2020-02-12 | — | — | EP | disclosed |