Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | GALR1 | P47211 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16878883 | 0.90 | NISCH (0.49) | NISCHGALR1KIF11EPHX2ALDH1A1 | |
| SCHEMBL14894193 | 0.81 | NISCH (0.50) | NISCHGALR1KIF11EPHX2TSHR | |
| SCHEMBL12473625 | 0.81 | WNT3A (0.46) | NISCHGALR1KIF11EPHX2SCN5A | |
| SCHEMBL12348393 | 0.76 | NISCH (0.41) | NISCHGALR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL254957 | 0.75 | MAPT (0.56) | NISCHKIF11EPHX2ALDH1A1TSHR | |
| SCHEMBL14893848 | 0.74 | NISCH (0.44) | NISCHGALR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL512312 | 0.73 | KCNH2 (0.44) | NISCHGALR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5146537 | 0.72 | KIF11 (0.48) | NISCHGALR1SLC6A3KIF11ALDH1A1 | |
| SCHEMBL7703942 | 0.72 | CA12 (0.50) | SLC6A3ALDH1A1 | |
| SCHEMBL5144843 | 0.72 | DRD1 (0.47) | SLC6A4ALDH1A1TSHRSCN5AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562878-B2 | Cycloalkylamines as monoamine reuptake inhibitors | SUNOVION PHARAMCEUTICALS INC. (US) | 2020-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562878-B2 | Cycloalkylamines as monoamine reuptake inhibitors | SLC18A2, SLC6A2, SLC18A3 | NISCH 871/4885GALR1 1113/4885SLC6A4 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.