Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.64 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 3/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.56 |
| ▸ | HTR1D | P28221 | 5/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATP4A | P20648 | 2/20 | 0.49 |
| ▸ | ATP4B | P51164 | 2/20 | 0.49 |
| ▸ | KIF20A | O95235 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19242898 | 0.83 | MEN1 (0.53) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL19412188 | 0.83 | MEN1 (0.53) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL12909375 | 0.81 | MEN1 (0.58) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL1791105 | 0.81 | MEN1 (0.60) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL10501049 | 0.80 | MEN1 (0.59) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL10501064 | 0.80 | MEN1 (0.59) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL9022913 | 0.78 | ALDH1A1 (0.55) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL15323122 | 0.77 | MEN1 (0.58) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL15325653 | 0.77 | MEN1 (0.58) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL28506218 | 0.77 | TRPM8 (0.64) | MEN1KMT2AGAAGPR55TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014936-B2 | Selective estrogen receptor degraders and uses thereof | INVENTISBIO LLC (US) | 2021-05-25 | — | — | US | disclosed |
| US-20200048250-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADERS AND USES THEREOF | INVENTISBIO LLC | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048250-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADERS AND USES THEREOF | ESR1, ESRRA, ESR2 | MEN1 3338/4885KMT2A 1662/4885GAA 305/4885 |
| US-11014936-B2 | Selective estrogen receptor degraders and uses thereof | ESR1, ESRRA, ESR2 | MEN1 3338/4885KMT2A 1662/4885GAA 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.