Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HTR1D | P28221 | 5/20 | 0.57 |
| ▸ | LTA4H | P09960 | 4/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10501049 | 0.85 | MEN1 (0.59) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL10501064 | 0.85 | MEN1 (0.59) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL1791105 | 0.84 | MEN1 (0.60) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL15325653 | 0.83 | MEN1 (0.58) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL15323122 | 0.83 | MEN1 (0.58) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL21701191 | 0.81 | MEN1 (0.64) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL9022913 | 0.81 | ALDH1A1 (0.55) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL12614535 | 0.80 | TRPM8 (0.61) | MEN1KMT2ATRPM8MAPTKDM4E | |
| SCHEMBL2004881 | 0.80 | TRPM8 (0.64) | MEN1KMT2AGAAGPR55TRPM8 | |
| SCHEMBL13947142 | 0.78 | ALDH1A1 (0.69) | MEN1KMT2AGAATRPM8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9486497-B2 | Treatment of immunocompromised conditions | THE UNIVERSITY OF QUEENSLAND (AU) | 2016-11-08 | — | — | US | disclosed |
| US-20160193294-A1 | COMPOSITIONS COMPRISING E-SELECTIN ANTAGONISTS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2016-07-07 | — | — | US | disclosed |
| US-20110002881-A1 | TREATMENT AND PROPHYLAXIS | MATER MEDICAL RESEARCH INSTITUTE (AU) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110002881-A1 | TREATMENT AND PROPHYLAXIS | SELP, SELE, SELPLG | MEN1 1414/4885KMT2A 2644/4885GAA 2077/4885 |
| US-20160193294-A1 | COMPOSITIONS COMPRISING E-SELECTIN ANTAGONISTS AND USES THEREFOR | SELL, SELP, SELE | MEN1 1930/4885KMT2A 3656/4885GAA 1907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.