Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30222070 | 1.00 | NSD2 (0.41) | NSD2MEN1NPC1KMT2AS1PR1 | |
| SCHEMBL21693648 | 0.90 | MEN1 (0.43) | NSD2MEN1NPC1KMT2AS1PR1 | |
| SCHEMBL29857502 | 0.89 | NSD2 (0.41) | NSD2MEN1NPC1KMT2AS1PR1 | |
| SCHEMBL21705018 | 0.88 | S1PR1 (0.43) | KMT2AS1PR1SIGMAR1MLYCDGPBAR1 | |
| SCHEMBL30222004 | 0.88 | S1PR1 (0.43) | KMT2AS1PR1SIGMAR1MLYCDGPBAR1 | |
| SCHEMBL24588307 | 0.87 | HCRTR1 (0.35) | NSD2S1PR1CYP11B1PDK2OXTR | |
| SCHEMBL29740342 | 0.87 | HCRTR1 (0.35) | NSD2S1PR1CYP11B1PDK2OXTR | |
| SCHEMBL21704816 | 0.87 | S1PR1 (0.49) | S1PR1OXTRGPBAR1LPAR1LPAR5 | |
| SCHEMBL21693657 | 0.87 | NSD2 (0.39) | NSD2MEN1NPC1KMT2AS1PR1 | |
| SCHEMBL21693611 | 0.87 | S1PR1 (0.39) | S1PR1OXTRGPBAR1LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816150-B1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CAC SHANGHAI INT TRADING CO LTD (CN) | 2024-07-24 | — | — | EP | disclosed |
| US-20230020373-A1 | 3-N-CYCLOPROPYLMETHYL-2-FLUOROBENZAMIDE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | CAC NANTONG CHEMICAL CO., LTD (CN) | 2023-01-19 | — | — | US | disclosed |
| US-11540516-B2 | M-diamide compound and preparation method therefor and use thereof | CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| US-11540516-B2 | M-diamide compound and preparation method therefor and use thereof | CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| EP-3816150-A1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Cac Shanghai International Trading Co., Ltd. (CN) | 2021-05-05 | — | — | EP | disclosed |
| EP-3816150-A1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Cac Shanghai International Trading Co., Ltd. (CN) | 2021-05-05 | — | — | EP | disclosed |
| WO-2021078293-A1 | 3-N-CYCLOPROPYLMETHYL-2-FLUOROBENZAMIDE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 南通泰禾化工股份有限公司 | 2021-04-29 | — | — | WO | disclosed |
| US-20200178525-A1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREOF AND USE THEREOF | CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) | 2020-06-11 | — | — | US | disclosed |
| US-20200178525-A1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREOF AND USE THEREOF | CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) | 2020-06-11 | — | — | US | disclosed |
| WO-2020030094-A1 | PHARMACEUTICAL COMPOSITION COMPRISING META-DIAMIDE COMPOUND AND USE THEREOF | 上海泰禾国际贸易有限公司 | 2020-02-13 | — | — | WO | disclosed |
| WO-2020030092-A1 | PHARMACEUTICAL COMPOSITION CONTAINING M-DIAMIDE COMPOUND AND APPLICATION THEREOF | 上海泰禾国际贸易有限公司 | 2020-02-13 | — | — | WO | disclosed |
| WO-2020030095-A1 | PHARMACEUTICAL COMPOSITION CONTAINING META-DIAMIDE COMPOUND AND USE THEREOF | 上海泰禾国际贸易有限公司 | 2020-02-13 | — | — | WO | disclosed |
| WO-2020030096-A1 | DRUG COMPOSITION CONTAINING M-DIAMIDE COMPOUND AND APPLICATION OF DRUG COMPOSITION | 上海泰禾国际贸易有限公司 | 2020-02-13 | — | — | WO | disclosed |
| WO-2020030093-A1 | PHARMACEUTICAL COMPOSITION CONTAINING M-DIAMIDE COMPOUND AND APPLICATION THEREOF | 上海泰禾国际贸易有限公司 | 2020-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11540516-B2 | M-diamide compound and preparation method therefor and use thereof | DIMT1, DDT, MRM1 | NSD2 1694/4885MEN1 99/4885NPC1 2530/4885 |
| US-20200178525-A1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREOF AND USE THEREOF | DDT, DIMT1, QDPR | NSD2 1386/4885MEN1 143/4885NPC1 2353/4885 |
| US-20230020373-A1 | 3-N-CYCLOPROPYLMETHYL-2-FLUOROBENZAMIDE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | CYP51A1, DDT, CYP4F11 | NSD2 1687/4885MEN1 504/4885NPC1 1956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.