Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30222004 | 1.00 | S1PR1 (0.43) | S1PR1ACHEAGERMTNR1AGPBAR1 | |
| SCHEMBL21704816 | 0.92 | S1PR1 (0.49) | S1PR1AGERGPBAR1LPAR1LPAR5 | |
| SCHEMBL21693611 | 0.92 | S1PR1 (0.39) | S1PR1ACHEGPBAR1LPAR1LPAR5 | |
| SCHEMBL21705017 | 0.89 | S1PR1 (0.41) | S1PR1ACHEAGERMTNR1AHSD17B10 | |
| SCHEMBL30221925 | 0.89 | S1PR1 (0.41) | S1PR1ACHEAGERMTNR1AHSD17B10 | |
| SCHEMBL21701267 | 0.89 | GPBAR1 (0.43) | S1PR1GPBAR1HDAC8HCRTR1HCRTR2 | |
| SCHEMBL29857251 | 0.88 | S1PR1 (0.41) | S1PR1ACHEAGERMTNR1AHSD17B10 | |
| SCHEMBL30222070 | 0.88 | NSD2 (0.41) | S1PR1GPBAR1LPAR1LPAR5HDAC8 | |
| SCHEMBL21701240 | 0.88 | NSD2 (0.41) | S1PR1GPBAR1LPAR1LPAR5HDAC8 | |
| SCHEMBL29180257 | 0.85 | CYP1A2 (0.42) | S1PR1ACHELPAR1LPAR5HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798108-A | Preparation method of inner-ring profenofos and intermediate thereof in micro-channel | 福州大学 | 2025-04-11 | — | — | CN | claimed |
| CN-116178198-A | Preparation method of cyflufenapyr | 南通泰禾化工股份有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-119798108-A | Preparation method of inner-ring profenofos and intermediate thereof in micro-channel | 福州大学 | 2025-04-11 | — | — | CN | disclosed |
| EP-3816150-B1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CAC SHANGHAI INT TRADING CO LTD (CN) | 2024-07-24 | — | — | EP | disclosed |
| CN-116178198-A | Preparation method of cyflufenapyr | 南通泰禾化工股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-115872889-A | Method for preparing o-trifluoromethylaniline compound | 沈阳中化农药化工研发有限公司 | 2023-03-31 | — | — | CN | disclosed |
| US-11540516-B2 | M-diamide compound and preparation method therefor and use thereof | CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| US-11540516-B2 | M-diamide compound and preparation method therefor and use thereof | CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| CN-113767907-B | Pharmaceutical composition containing m-diamide compounds and application thereof | 南通泰禾化工股份有限公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-113767908-B | Pharmaceutical composition containing m-diamide compound and application thereof | 南通泰禾化工股份有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-110810410-B | Pharmaceutical composition containing m-diamide compound and application thereof | 南通泰禾化工股份有限公司 | 2022-02-11 | — | — | CN | disclosed |
| US-20200178525-A1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREOF AND USE THEREOF | CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) | 2020-06-11 | — | — | US | disclosed |
| US-20200178525-A1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREOF AND USE THEREOF | CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) | 2020-06-11 | — | — | US | disclosed |
| CN-110810414-A | Pharmaceutical composition containing m-diamide compound and application thereof | 苏州佳辉化工有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-110810413-A | Pharmaceutical composition containing m-diamide compound and application thereof | 上海泰禾国际贸易有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-110810409-A | Pharmaceutical composition containing m-diamide compound and application thereof | 上海泰禾国际贸易有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-110810410-A | Pharmaceutical composition containing m-diamide compound and application thereof | 上海泰禾国际贸易有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-110810412-A | Pharmaceutical composition containing m-diamide compound and application thereof | 苏州佳辉化工有限公司 | 2020-02-21 | — | — | CN | disclosed |
| WO-2020030092-A1 | PHARMACEUTICAL COMPOSITION CONTAINING M-DIAMIDE COMPOUND AND APPLICATION THEREOF | 上海泰禾国际贸易有限公司 | 2020-02-13 | — | — | WO | disclosed |
| WO-2020030094-A1 | PHARMACEUTICAL COMPOSITION COMPRISING META-DIAMIDE COMPOUND AND USE THEREOF | 上海泰禾国际贸易有限公司 | 2020-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11540516-B2 | M-diamide compound and preparation method therefor and use thereof | DIMT1, DDT, MRM1 | S1PR1 3653/4885ACHE 72/4885AGER 864/4885 |
| US-20200178525-A1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREOF AND USE THEREOF | DDT, DIMT1, QDPR | S1PR1 3752/4885ACHE 24/4885AGER 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.