Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.37 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.36 |
| ▸ | PEPD | P12955 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651427 | 0.81 | — | — | |
| SCHEMBL352246 | 0.80 | GABRR1 (0.59) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| SCHEMBL7150608 | 0.80 | GABRR1 (0.59) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| SCHEMBL2135258 | 0.80 | GABRR1 (0.59) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| SCHEMBL20346208 | 0.80 | GABRR1 (0.59) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| SCHEMBL6938207 | 0.80 | GABRR1 (0.59) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| SCHEMBL709492 | 0.80 | GABRR1 (0.59) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| SCHEMBL339332 | 0.80 | GABRR1 (0.59) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| SCHEMBL4979720 | 0.78 | SMN1; SMN2 (0.40) | — | |
| Hydrochloric Acid SCHEMBL8452138 | 0.76 | GABRR1 (0.56) | GABRR1SLC1A2SLC1A1GABRR2PEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030826-A1 | COMPOUNDS FOR MODULATION AND AS FUNCTIONAL REPLACEMENT OF ALPHA-KETOGLUTARIC ACID (2OG)-DEPENDENT OXYGENASES | HOMANN THOMAS MELCHIOR (DE) | 2020-02-13 | — | — | WO | disclosed |