SCHEMBL352246

SCHEMBL352246

O=C(O)[C@@H]1CC[C@H]1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.59
SLC1A2 P43004 3/20 0.48
SLC1A1 P43005 2/20 0.48
GABRR2 P28476 1/20 0.48
PEPD P12955 1/20 0.46
CYP2D6 P10635 2/20 0.44
LMNA P02545 2/20 0.44
BLM P54132 2/20 0.44
CYP2C19 P33261 2/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
CYP1A2 P05177 1/20 0.44
RAB9A P51151 1/20 0.44
MEN1 O00255 1/20 0.44
THRB P10828 1/20 0.44
PMP22 Q01453 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7150608 1.00 GABRR1 (0.59) GABRR1SLC1A2SLC1A1GABRR2PEPD
SCHEMBL2135258 1.00 GABRR1 (0.59) GABRR1SLC1A2SLC1A1GABRR2PEPD
SCHEMBL20346208 1.00 GABRR1 (0.59) GABRR1SLC1A2SLC1A1GABRR2PEPD
SCHEMBL709492 1.00 GABRR1 (0.59) GABRR1SLC1A2SLC1A1GABRR2PEPD
SCHEMBL6938207 1.00 GABRR1 (0.59) GABRR1SLC1A2SLC1A1GABRR2PEPD
SCHEMBL339332 1.00 GABRR1 (0.59) GABRR1SLC1A2SLC1A1GABRR2PEPD
Hydrochloric Acid SCHEMBL8452138 0.96 GABRR1 (0.56) GABRR1SLC1A2SLC1A1GABRR2PEPD
Hydrochloric Acid SCHEMBL8942934 0.96 GABRR1 (0.56) GABRR1SLC1A2SLC1A1GABRR2PEPD
Hydrochloric Acid SCHEMBL8942927 0.96 GABRR1 (0.56) GABRR1SLC1A2SLC1A1GABRR2PEPD
Hydrochloric Acid SCHEMBL8452135 0.96 GABRR1 (0.56) GABRR1SLC1A2SLC1A1GABRR2PEPD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010757-A Process for preparing trans-cyclobutane-1, 2-dicarboxamide 海南长安国际制药有限公司 2026-05-12 CN claimed
CN-114835570-A Synthesis method of trans-1, 2-diaminomethyl-cyclobutane and salt thereof 上海寻科生物医药科技有限公司 2022-08-02 CN claimed
US-20090286291-A1 BORRELIDIN-PRODUCING POLYKETIDE SYNTHASE AND ITS USE SALAS JOSE A 2009-11-19 US claimed
EP-1961747-A2 Borrelidin-producing polyketide synthase and its uses Biotica Technology Limited (GB) 2008-08-27 EP claimed
EP-1840216-A2 Borrelidin-producing polyketides synthase and its uses Biotica Technology Limited (GB) 2007-10-03 EP claimed
EP-1576160-B8 BORRELIDIN-DERIVATIVES AND THEIR USE IN MEDICINE BIOTICA TECH LTD (GB) 2007-06-27 EP claimed
US-20070065920-A1 For treatment of microbial conditions (including malaria), proliferative disorders, inappropiate vascularisation, inhibition of angiogenesis; THE UNIVERSITY OF OVIEDO (ES) 2007-03-22 US claimed
EP-1576160-A2 BORRELIDIN-PRODUCING POLYKETIDE SYNTHASE AND ITS USE Biotica Technology Limited (GB) 2005-09-21 EP claimed
WO-2004058976-A2 BORRELIDIN-PRODUCING POLYKETIDE SYNTHASE AND ITS USE BIOTICA TECHNOLOGY LIMITED (GB) 2004-07-15 WO claimed
EP-0543264-B1 Rewritable thermosensitive recording medium TOPPAN PRINTING CO LTD (JP) 1995-05-03 EP claimed
US-5278129-A Low molecular weight alicyclic dicarboxylic acid TOPPAN PRINTING CO., LTD. (JP) 1994-01-11 US claimed
EP-0543264-A1 Rewritable thermosensitive recording medium Toppan Printing Co., Ltd. (JP) 1993-05-26 EP claimed
EP-0130482-B1 DIAMINOCYCLOHEXANE PLATINUM COMPLEXES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Research Corporation (US) 1988-12-28 EP claimed
US-4758588-A Diaminocyclohexane platinum complexes RESEARCH CORPORATION TECHNOLOGIES (US) 1988-07-19 US claimed
US-4661516-A WATER SOLUBLE, ANTITUMOR AGENTS RESEARCH CORPORATION (US) 1987-04-28 US claimed
EP-0130482-A1 Diaminocyclohexane platinum complexes, process for preparing same and pharmaceutical compositions containing same Research Corporation (US) 1985-01-09 EP claimed
US-4230860-A Processes for the separation of enantiomers by selective crystallization AMERICAN CYANAMID COMPANY (US) 1980-10-28 US claimed
CN-122029149-A 3- (2- (Dimethylamino) ethyl) -1H-indol-4-yl oligoderivatives 指南针探路者有限公司 2026-05-12 CN disclosed
US-3978101-A HYDROGENATION CATALYSTS RHONE-POULENC S.A. (FR) 1976-08-31 US disclosed
US-3949000-A COMPLEX FORMERS RHONE-POULENC S.A. (FR) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070065920-A1 For treatment of microbial conditions (including malaria), proliferative disorders, inappropiate vascularisation, inhibition of angiogenesis; COASY, FDPS, FLAD1 GABRR1 3253/4885SLC1A2 4580/4885SLC1A1 4387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.