Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.59 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.48 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.48 |
| ▸ | PEPD | P12955 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352246 | 1.00 | GABRR1 (0.59) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| SCHEMBL2135258 | 1.00 | GABRR1 (0.59) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| SCHEMBL20346208 | 1.00 | GABRR1 (0.59) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| SCHEMBL709492 | 1.00 | GABRR1 (0.59) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| SCHEMBL6938207 | 1.00 | GABRR1 (0.59) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| SCHEMBL339332 | 1.00 | GABRR1 (0.59) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| Hydrochloric Acid SCHEMBL8452138 | 0.96 | GABRR1 (0.56) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| Hydrochloric Acid SCHEMBL8942934 | 0.96 | GABRR1 (0.56) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| Hydrochloric Acid SCHEMBL8942927 | 0.96 | GABRR1 (0.56) | GABRR1SLC1A2SLC1A1GABRR2PEPD | |
| Hydrochloric Acid SCHEMBL8452135 | 0.96 | GABRR1 (0.56) | GABRR1SLC1A2SLC1A1GABRR2PEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186822-A1 | PHARMACEUTICAL CO-CRYSTAL COMPOSITION AND USE THEREOF | Syn-Nat Products Enterprise LLC | 2018-07-05 | — | — | US | disclosed |
| EP-3297624-A1 | A PHARMACEUTICAL CO-CRYSTAL AND USE THEREOF | Syn-Nat Products Enterprise LLC (US) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016187191-A1 | A PHARMACEUTICAL CO-CRYSTAL AND USE THEREOF | Medoc Pharmaceutical Co., Ltd. (CN) | 2016-11-24 | — | — | WO | disclosed |
| EP-1357910-A2 | METHOD FOR PREVENTING AND TREATING VISCERAL PAIN AND GASTROINTESTINAL DISORDERS | Warner-Lambert Company LLC (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002058680-A2 | USE OF BICYLIC AMINO ACIDS FOR PREVENTING AND TREATING VISCERAL PAIN AND GASTROINTESTINAL DISORDERS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186822-A1 | PHARMACEUTICAL CO-CRYSTAL COMPOSITION AND USE THEREOF | CXCR3, CCR3, CCR5 | GABRR1 4159/4885SLC1A2 2654/4885SLC1A1 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.