SCHEMBL2135258

SCHEMBL2135258

O=C(O)C1CCC(C(=O)O)C(C(=O)O)CCC1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.59
SLC1A2 P43004 3/20 0.48
SLC1A1 P43005 2/20 0.48
GABRR2 P28476 1/20 0.48
PEPD P12955 1/20 0.46
CYP2D6 P10635 2/20 0.44
LMNA P02545 2/20 0.44
BLM P54132 2/20 0.44
CYP2C19 P33261 2/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
CYP1A2 P05177 1/20 0.44
RAB9A P51151 1/20 0.44
MEN1 O00255 1/20 0.44
THRB P10828 1/20 0.44
PMP22 Q01453 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7150608 1.00 GABRR1 (0.59) GABRR1SLC1A2SLC1A1GABRR2PEPD
SCHEMBL352246 1.00 GABRR1 (0.59) GABRR1SLC1A2SLC1A1GABRR2PEPD
SCHEMBL20346208 1.00 GABRR1 (0.59) GABRR1SLC1A2SLC1A1GABRR2PEPD
SCHEMBL709492 1.00 GABRR1 (0.59) GABRR1SLC1A2SLC1A1GABRR2PEPD
SCHEMBL6938207 1.00 GABRR1 (0.59) GABRR1SLC1A2SLC1A1GABRR2PEPD
SCHEMBL339332 1.00 GABRR1 (0.59) GABRR1SLC1A2SLC1A1GABRR2PEPD
Hydrochloric Acid SCHEMBL8452138 0.96 GABRR1 (0.56) GABRR1SLC1A2SLC1A1GABRR2PEPD
Hydrochloric Acid SCHEMBL8942934 0.96 GABRR1 (0.56) GABRR1SLC1A2SLC1A1GABRR2PEPD
Hydrochloric Acid SCHEMBL8942927 0.96 GABRR1 (0.56) GABRR1SLC1A2SLC1A1GABRR2PEPD
Hydrochloric Acid SCHEMBL8452135 0.96 GABRR1 (0.56) GABRR1SLC1A2SLC1A1GABRR2PEPD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024125945-A1 COMPOSITION FOR FORMING A LIQUID CRYSTAL ALIGNMENT FILM Rolic Technologies AG (CH) 2024-06-20 WO disclosed
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
CN-110392725-B Photoalignment composition for stabilizing pretilt angle in liquid crystal layer 罗利克技术有限公司 2023-12-01 CN disclosed
CN-110871606-B Metal-clad laminate, adhesive sheet, adhesive polyimide resin composition, and circuit board 日铁化学材料株式会社 2023-05-16 CN disclosed
US-11634544-B2 Photoaligning materials Rolic Technologies AG (CH) 2023-04-25 US disclosed
US-11561440-B2 Photoalignment composition for the stabilization of the pre-tilt angle in liquid crystal layers Rolic Technologies AG (CH) 2023-01-24 US disclosed
CN-115122735-A Polyimide, resin composition, resin film, laminate, coverlay film, resin-coated copper foil, metal-clad laminate, and circuit board 日铁化学材料株式会社 2022-09-30 CN disclosed
US-20210340330-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2021-11-04 US disclosed
EP-3628054-B1 NEW PHOTOALIGNMENT COMPOSITION FOR THE STABILIZATION OF THE PRE-TILT ANGLE IN LIQUID CRYSTAL LAYERS ROLIC TECH AG (CH) 2021-10-06 EP disclosed
US-20200223984-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2020-07-16 US disclosed
WO-2011131649-A1 PHOTOALIGNING MATERIAL ROLIC AG (CH) 2011-10-27 WO disclosed
WO-2011098461-A1 PHOTOALIGNING MATERIAL WITH LATERAL SUBSTITUTION ROLIC AG (CH) 2011-08-18 WO disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
CN-101687991-A Thermally stable alignment materials ROLIC AG 2010-03-31 CN disclosed
CN-101687763-A Photocrosslinkable materials comprising alicyclic group ROLIC AG 2010-03-31 CN disclosed
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2010-02-25 US disclosed
EP-2152660-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP Rolic AG (CH) 2010-02-17 EP disclosed
EP-2144951-A1 THERMALLY STABLE ALIGNMENT MATERIALS Rolic AG (CH) 2010-01-20 EP disclosed
WO-2008145225-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2008-12-04 WO disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP DDC, ALAD, DYNC1LI1 GABRR1 2954/4885SLC1A2 398/4885SLC1A1 303/4885
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS PARG, PARN, PUF60 GABRR1 3029/4885SLC1A2 213/4885SLC1A1 197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.