Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.54 |
| ▸ | CTSB | P07858 | 4/20 | 0.54 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23711179 | 1.00 | CTSL (0.54) | CTSLCTSBCTSS | |
| SCHEMBL23506277 | 0.96 | CTSB (0.52) | CTSLCTSBCTSS | |
| SCHEMBL21702350 | 0.96 | CTSB (0.52) | CTSLCTSBCTSS | |
| SCHEMBL21702354 | 0.92 | CTSL (0.54) | CTSLCTSBCTSS | |
| SCHEMBL23506404 | 0.92 | CTSL (0.54) | CTSLCTSBCTSS | |
| SCHEMBL23506462 | 0.90 | CTSL (0.53) | CTSLCTSBCTSS | |
| SCHEMBL21702355 | 0.90 | CTSL (0.53) | CTSLCTSBCTSS | |
| SCHEMBL21702321 | 0.88 | PYGL (0.54) | CTSLCTSB | |
| SCHEMBL23506311 | 0.88 | PYGL (0.54) | CTSLCTSB | |
| SCHEMBL21702349 | 0.88 | CTSB (0.52) | CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151387-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | 中国科学院上海药物研究所 | 2021-08-05 | — | — | WO | disclosed |
| EP-3835296-A1 | KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-06-16 | — | — | EP | disclosed |
| WO-2020030143-A1 | KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 中国科学院上海药物研究所 | 2020-02-13 | — | — | WO | disclosed |