Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2350978 | 0.84 | TRPV1 (0.47) | ALDH1A1MAPTTSHRGAAKDM4E | |
| SCHEMBL1374082 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPTTSHRGAAKDM4E | |
| SCHEMBL1374084 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPTTSHRGAAKDM4E | |
| SCHEMBL4006650 | 0.82 | ALDH1A1 (0.93) | ALDH1A1MAPTTSHRGAAKDM4E | |
| SCHEMBL2171615 | 0.80 | ALDH1A1 (0.51) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL2172990 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL2171842 | 0.80 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2169800 | 0.80 | ALDH1A1 (0.51) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL2170390 | 0.80 | SMN1; SMN2 (0.56) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL2357200 | 0.79 | S1PR1 (0.48) | ALDH1A1MAPTKDM4EKMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346821-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | Exelixis, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |