Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171615 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL2171842 | 0.83 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1ATMHPGD | |
| SCHEMBL2169800 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL2170390 | 0.82 | SMN1; SMN2 (0.56) | ALDH1A1LMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL2170428 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL1372461 | 0.81 | S1PR1 (0.63) | ALDH1A1LMNASMN1; SMN2GAAS1PR1 | |
| SCHEMBL1372463 | 0.81 | S1PR1 (0.63) | ALDH1A1LMNASMN1; SMN2GAAS1PR1 | |
| SCHEMBL2170253 | 0.80 | ALDH1A1 (0.67) | ALDH1A1LMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL2171620 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2GAACYP3A4CYP2D6 | |
| SCHEMBL2185321 | 0.79 | IDO1 (0.47) | ALDH1A1LMNASMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346821-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | Exelixis, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |