Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | GABRE | P78334 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21702875 | 0.88 | ALDH1A1 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15623792 | 0.84 | SLC1A3 (0.38) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL12582831 | 0.80 | HCAR2 (0.39) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL12583052 | 0.80 | HCAR2 (0.39) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL16670927 | 0.80 | SLC7A5 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3714789 | 0.79 | PTGS1 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7599853 | 0.79 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7599850 | 0.79 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25199857 | 0.78 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13559328 | 0.78 | SLC1A3 (0.34) | SLC1A3SLC1A2SLC1A1GSRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030663-A1 | CLEAVABLE LINKER FOR PEPTIDE SYNTHESIS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-02-13 | — | — | WO | disclosed |