SCHEMBL21702875

SCHEMBL21702875

CCC(N)C(=O)OCCCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
AKR1B1 P15121 1/20 0.40
NOD1 Q9Y239 1/20 0.39
GPR84 Q9NQS5 7/20 0.39
PPARG P37231 7/20 0.39
PPARD Q03181 7/20 0.39
PPARA Q07869 7/20 0.39
HDAC11 Q96DB2 5/20 0.39
TSHR P16473 4/20 0.39
PTPN1 P18031 3/20 0.39
TLR2 O60603 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
FABP4 P15090 2/20 0.39
SLC22A6 Q4U2R8 1/20 0.39
SLC22A8 Q8TCC7 1/20 0.39
MEN1 O00255 1/20 0.39
ESR1 P03372 1/20 0.39
ALOX15 P16050 1/20 0.39
PDE4A P27815 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21702870 0.88 GABRP (0.40) ALDH1A1AKR1B1NOD1GABRPGABRD
SCHEMBL21702868 0.85 ALDH1A1 (0.51) ALDH1A1AKR1B1NOD1GPR84PPARG
SCHEMBL2734881 0.82 ALDH1A1 (0.52) ALDH1A1NOD1TSHRTDP1ESR1
SCHEMBL2734865 0.82 ALDH1A1 (0.52) ALDH1A1NOD1TSHRTDP1ESR1
SCHEMBL9212582 0.81 SLC7A5 (0.48) ALDH1A1NOD1HDAC11TSHRSLC22A6
SCHEMBL15623792 0.81 SLC1A3 (0.38) ALDH1A1NOD1TSHRALOX15HSD17B10
SCHEMBL7599884 0.80 ALDH1A1 (0.42) ALDH1A1AKR1B1GPR84PPARGPPARD
SCHEMBL7599881 0.80 ALDH1A1 (0.42) ALDH1A1AKR1B1GPR84PPARGPPARD
SCHEMBL2123202 0.80 NOD1 (0.51) ALDH1A1AKR1B1NOD1GPR84PPARG
SCHEMBL18686280 0.80 GABRP (0.45) ALDH1A1AKR1B1GPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020030663-A1 CLEAVABLE LINKER FOR PEPTIDE SYNTHESIS F. HOFFMANN-LA ROCHE AG (CH) 2020-02-13 WO disclosed