Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 5/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21684760 | 0.89 | PPARG (0.41) | PPARGDGAT1VCPNPC1L3MBTL1 | |
| SCHEMBL21703014 | 0.86 | NPC1 (0.38) | PPARGDGAT1VCPNPC1L3MBTL1 | |
| SCHEMBL21684905 | 0.85 | NPC1 (0.36) | PPARGDGAT1VCPNPC1L3MBTL1 | |
| SCHEMBL23453074 | 0.84 | VCP (0.38) | DGAT1VCPNPC1L3MBTL1TSHR | |
| SCHEMBL24859760 | 0.83 | VCP (0.38) | DGAT1VCPNPC1L3MBTL1 | |
| SCHEMBL21684567 | 0.83 | DGAT1 (0.39) | PPARGDGAT1NPC1TLR8 | |
| SCHEMBL21684696 | 0.83 | F11 (0.41) | PPARGDGAT1VCPNPC1 | |
| SCHEMBL21685317 | 0.83 | VCP (0.37) | PPARGDGAT1VCPNPC1L3MBTL1 | |
| SCHEMBL21684454 | 0.82 | F11 (0.35) | PPARGDGAT1VCPNPC1TLR8 | |
| SCHEMBL21684566 | 0.81 | F11 (0.38) | PPARGDGAT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033784-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | SITARI PHARMA, INC. (US) | 2020-02-13 | — | — | WO | disclosed |