Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20408267 | 0.94 | SIGMAR1 (0.53) | SLC6A4SIGMAR1TAAR1SLC6A2SLC6A3 | |
| SCHEMBL3462477 | 0.88 | TAAR1 (0.59) | SLC6A4SIGMAR1TAAR1SLC6A2SLC6A3 | |
| SCHEMBL23159850 | 0.80 | ALOX15 (0.47) | SIGMAR1TAAR1 | |
| SCHEMBL23159894 | 0.80 | ALOX15 (0.47) | SIGMAR1TAAR1HTR2A | |
| SCHEMBL27791791 | 0.79 | SIGMAR1 (0.41) | SIGMAR1AOC3 | |
| SCHEMBL9670821 | 0.79 | SIGMAR1 (0.63) | SLC6A4SIGMAR1TAAR1HTR2AHRH1 | |
| SCHEMBL23159817 | 0.78 | SIGMAR1 (0.46) | SIGMAR1TAAR1 | |
| SCHEMBL6004011 | 0.78 | SIGMAR1 (0.46) | SIGMAR1TAAR1HTR2A | |
| SCHEMBL30929931 | 0.78 | SIGMAR1 (0.46) | SIGMAR1TAAR1HTR2A | |
| SCHEMBL14875929 | 0.77 | NOS1 (0.40) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184078-A1 | Ligand Functionalized Substrates | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2011-07-28 | — | — | US | disclosed |