Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21703561 | 0.89 | LMNA (0.33) | PDE4DLMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL21678316 | 0.87 | LMNA (0.34) | PDE4DLMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL19994255 | 0.85 | SCN9A (0.38) | PDE4DLMNASMN1; SMN2PKMCYP1A2 | |
| SCHEMBL19994252 | 0.84 | LMNA (0.35) | PDE4DLMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL18529636 | 0.84 | LMNA (0.44) | PDE4DLMNASMN1; SMN2PKMTSHR | |
| SCHEMBL21678311 | 0.83 | LMNA (0.36) | PDE4DLMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL21678324 | 0.83 | ALDH1A1 (0.36) | PDE4DLMNASMN1; SMN2PKMCYP1A2 | |
| SCHEMBL21678314 | 0.80 | PDE4D (0.37) | PDE4DLMNASMN1; SMN2PKMCYP3A4 | |
| SCHEMBL19994248 | 0.71 | LMNA (0.48) | PDE4DLMNASMN1; SMN2PKMTSHR | |
| SCHEMBL30172138 | 0.66 | LMNA (0.47) | PDE4DLMNASMN1; SMN2PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200045967-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200045967-A1 | NOVEL TRIAZOLE DERIVATIVES | CYP51A1, ERG28, SBK3 | PDE4D 1793/4885LMNA 4224/4885SMN1; SMN2 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.