⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21704052 | 0.75 | — | — | |
| SCHEMBL19099831 | 0.73 | — | — | |
| SCHEMBL22702460 | 0.73 | — | — | |
| SCHEMBL19098311 | 0.73 | — | — | |
| SCHEMBL21704246 | 0.70 | — | — | |
| SCHEMBL19098322 | 0.70 | GBA1 (0.40) | — | |
| SCHEMBL21746450 | 0.69 | — | — | |
| SCHEMBL22962280 | 0.69 | SI (0.33) | — | |
| SCHEMBL5773307 | 0.69 | SLC6A12 (0.35) | — | |
| SCHEMBL1586267 | 0.69 | SLC6A12 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033707-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2020-02-13 | — | — | WO | disclosed |