Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 7/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722574 | 0.86 | CA1 (0.43) | CA1CA2ACHEALDH1A1GAA | |
| SCHEMBL21685672 | 0.80 | CA1 (0.49) | CA1CA2ACHEALDH1A1GAA | |
| SCHEMBL20722774 | 0.80 | CA1 (0.49) | CA1CA2ACHEALDH1A1GAA | |
| SCHEMBL23938263 | 0.77 | CA1 (0.44) | CA1CA2ACHEALDH1A1GAA | |
| SCHEMBL28572866 | 0.77 | CA1 (0.44) | CA1CA2ACHEALDH1A1GAA | |
| SCHEMBL30968421 | 0.77 | CA1 (0.44) | CA1CA2ACHEALDH1A1GAA | |
| SCHEMBL20722877 | 0.76 | CA1 (0.46) | CA1CA2ACHEALDH1A1GAA | |
| SCHEMBL21685740 | 0.76 | ACHE (0.47) | CA1CA2ACHEALDH1A1CTSL | |
| SCHEMBL20722476 | 0.76 | ACHE (0.47) | CA1CA2ACHEALDH1A1CTSL | |
| SCHEMBL21685806 | 0.75 | CA1 (0.43) | CA1CA2ACHEALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033707-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2020-02-13 | — | — | WO | disclosed |