Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | GALR1 | P47211 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20732039 | 0.82 | KIT (0.42) | GPR119ALDH1A1ALKTLR9DPP4 | |
| SCHEMBL20723028 | 0.82 | KIT (0.42) | GPR119ALDH1A1ALKTLR9DPP4 | |
| SCHEMBL30059936 | 0.82 | KIT (0.42) | GPR119ALDH1A1ALKTLR9DPP4 | |
| SCHEMBL21684984 | 0.80 | ACHE (0.45) | GPR119ALDH1A1TLR9KITMAPT | |
| SCHEMBL20722673 | 0.80 | ACHE (0.45) | GPR119ALDH1A1TLR9KITMAPT | |
| SCHEMBL30061862 | 0.74 | USP28 (0.52) | ALDH1A1MAPT | |
| SCHEMBL21684866 | 0.74 | USP28 (0.52) | ALDH1A1MAPT | |
| SCHEMBL20722457 | 0.74 | USP28 (0.52) | ALDH1A1MAPT | |
| SCHEMBL2414006 | 0.74 | GPR119 (0.47) | GPR119ALDH1A1ALKTLR9DPP4 | |
| SCHEMBL31264270 | 0.70 | EPHX1 (0.57) | GPR119ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033707-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2020-02-13 | — | — | WO | disclosed |