Formaldehyde

Formaldehyde

SCHEMBL2170447

C=O.O=C(C(F)(F)F)C(F)(F)F

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.37
CES2 O00748 1/20 0.35
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL10949111 0.92 CA2 (0.37) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL344 0.91 CA2 (0.41) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL27892503 0.91 CA2 (0.41) CA2CES2ALDH1A1POLBSMN1; SMN2
Water SCHEMBL581158 0.87 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
Fluoride SCHEMBL1594462 0.87 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL11421274 0.87 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
Water SCHEMBL18544564 0.87 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL7149277 0.87 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL11800353 0.87 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL9473581 0.87 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602662-B1 METHOD OF OBTAINING 17ALPHA-ACETOXY-11BETA-(4-N,N-DIMETHYLAMINOPHENYL)-19-NORPREGNA-4,9-DIENE-3,20-DIONE CRYSTAL PHARMA SAU (ES) 2014-04-23 EP disclosed
EP-2348033-A2 Process for obtaining 17alfa-acetoxy-11beta-(4-n,n-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione Crystal Pharma, S.L.U. (ES) 2011-07-27 EP disclosed
US-20060247452-A1 Method for obtaining 17sg(a)-acetoxy-11$g(b)-(4-n,n-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione CRYSTAL PHARMA, S.A. (ES) 2006-11-02 US disclosed
EP-1602662-A1 METHOD OF OBTAINING 17ALPHA-ACETOXY-11BETA-(4-N,N-DIMETHYLAMINOPHENYL)-19-NORPREGNA-4,9-DIENE-3,20-DIONE Crystal Pharma, S.A. (ES) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247452-A1 Method for obtaining 17sg(a)-acetoxy-11$g(b)-(4-n,n-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione HSD17B13, HSD17B11, HSD17B3 CA2 2670/4885CES2 2898/4885ALDH1A1 1085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.