Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29663926 | 0.77 | HPGD (0.30) | — | |
| SCHEMBL20818866 | 0.77 | VHL (0.42) | — | |
| SCHEMBL18914637 | 0.77 | CHRM1 (0.36) | CHRM1 | |
| SCHEMBL8128659 | 0.75 | — | — | |
| SCHEMBL6768555 | 0.74 | PPARA (0.34) | — | |
| SCHEMBL6769135 | 0.74 | NOTUM (0.58) | — | |
| SCHEMBL10341846 | 0.74 | — | — | |
| SCHEMBL19916741 | 0.73 | ALDH1A1 (0.37) | — | |
| SCHEMBL4349489 | 0.72 | PPARA (0.44) | CHRM1 | |
| SCHEMBL6774196 | 0.72 | RAB9A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346868-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010036632-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |