SCHEMBL21704705

SCHEMBL21704705

O=c1cc(-c2cc(Br)ccc2O)oc2cc(Cl)ccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TP53 P04637 1/20 0.54
ALOX15 P16050 1/20 0.54
GABRP O00591 4/20 0.48
GABRD O14764 4/20 0.48
GABRA1 P14867 4/20 0.48
GABRB1 P18505 4/20 0.48
GABRG2 P18507 4/20 0.48
GABRB3 P28472 4/20 0.48
GABRA5 P31644 4/20 0.48
GABRA3 P34903 4/20 0.48
GABRA2 P47869 4/20 0.48
GABRB2 P47870 4/20 0.48
GABRA4 P48169 4/20 0.48
GABRE P78334 4/20 0.48
GABRA6 Q16445 4/20 0.48
GABRG1 Q8N1C3 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21704790 0.90 HPGD (0.57) HPGDMEN1KMT2ASMN1; SMN2TP53
SCHEMBL8934652 0.87 GABRP (0.61) TP53GABRPGABRDGABRA1GABRB1
SCHEMBL21704890 0.82 AKR1C3 (0.71) HPGDMEN1KMT2ASMN1; SMN2TP53
SCHEMBL8934535 0.79 GABRP (0.62) HPGDSMN1; SMN2TP53GABRPGABRD
SCHEMBL21822751 0.79 MEN1 (0.48) HPGDMEN1KMT2ASMN1; SMN2TP53
SCHEMBL21822643 0.75 MEN1 (0.51) HPGDMEN1KMT2ASMN1; SMN2TP53
SCHEMBL22806467 0.74 HPGD (0.54) HPGDMEN1KMT2ASMN1; SMN2TP53
SCHEMBL21823061 0.73 MEN1 (0.44) HPGDMEN1KMT2ASMN1; SMN2ALOX15
SCHEMBL21704894 0.72 HPGD (0.74) HPGDMEN1KMT2ASMN1; SMN2TP53
SCHEMBL6244185 0.72 HPGD (0.62) HPGDMEN1KMT2ASMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11332474-B2 Compound and organic light-emission device LG DISPLAY CO., LTD. (KR) 2022-05-17 US disclosed
US-20200048273-A1 COMPOUND AND ORGANIC LIGHT-EMISSION DEVICE LG DISPLAY CO., LTD. (KR) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048273-A1 COMPOUND AND ORGANIC LIGHT-EMISSION DEVICE TRPC4, TRPA1, TRPC1 HPGD 3330/4885MEN1 2375/4885KMT2A 1629/4885
US-11332474-B2 Compound and organic light-emission device TRPC4, TRPA1, TRPC1 HPGD 3330/4885MEN1 2375/4885KMT2A 1629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.