Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 12/20 | 0.61 |
| ▸ | GABRD | O14764 | 12/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 12/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 12/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 12/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.61 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.61 |
| ▸ | GABRA3 | P34903 | 12/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.61 |
| ▸ | GABRA4 | P48169 | 12/20 | 0.61 |
| ▸ | GABRE | P78334 | 12/20 | 0.61 |
| ▸ | GABRA6 | Q16445 | 12/20 | 0.61 |
| ▸ | GABRG1 | Q8N1C3 | 12/20 | 0.61 |
| ▸ | GABRG3 | Q99928 | 12/20 | 0.61 |
| ▸ | GABRQ | Q9UN88 | 12/20 | 0.61 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.55 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934535 | 0.90 | GABRP (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21704705 | 0.87 | HPGD (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21704790 | 0.82 | HPGD (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8934553 | 0.81 | GABRP (0.64) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21704890 | 0.80 | AKR1C3 (0.71) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4649213 | 0.79 | GABRP (0.74) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6908632 | 0.77 | GABRP (0.71) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22806293 | 0.74 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21822751 | 0.73 | MEN1 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4988784 | 0.73 | MAPT (0.77) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |