SCHEMBL21705017

SCHEMBL21705017

O=C(O)c1cccc(N(CC2CC2)C(=O)c2ccc(F)cc2)c1F

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.41
LPAR1 Q92633 11/20 0.40
LPAR5 Q9H1C0 11/20 0.40
ACHE P22303 1/20 0.40
AGER Q15109 2/20 0.39
MTNR1A P48039 1/20 0.39
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
RECQL P46063 1/20 0.37
KMT2A Q03164 1/20 0.37
HCRTR1 O43613 1/20 0.37
HCRTR2 O43614 1/20 0.37
NFE2L2 Q16236 1/20 0.37
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30221925 1.00 S1PR1 (0.41) S1PR1LPAR1LPAR5ACHEAGER
SCHEMBL21693659 0.93 HDAC1 (0.40) S1PR1LPAR1LPAR5MEN1MAPT
SCHEMBL21704817 0.91 S1PR1 (0.49) S1PR1LPAR1LPAR5AGER
SCHEMBL30222004 0.89 S1PR1 (0.43) S1PR1LPAR1LPAR5ACHEAGER
SCHEMBL29857251 0.89 S1PR1 (0.41) S1PR1LPAR1LPAR5ACHEAGER
SCHEMBL21705018 0.89 S1PR1 (0.43) S1PR1LPAR1LPAR5ACHEAGER
SCHEMBL21701268 0.89 GPBAR1 (0.42) S1PR1LPAR1LPAR5
SCHEMBL21693648 0.88 MEN1 (0.43) S1PR1LPAR1LPAR5MEN1KMT2A
SCHEMBL29180257 0.86 CYP1A2 (0.42) S1PR1LPAR1LPAR5ACHEKMT2A
SCHEMBL30370555 0.86 CYP1A2 (0.42) S1PR1LPAR1LPAR5ACHEKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798108-A Preparation method of inner-ring profenofos and intermediate thereof in micro-channel 福州大学 2025-04-11 CN claimed
CN-116178198-A Preparation method of cyflufenapyr 南通泰禾化工股份有限公司 2023-05-30 CN claimed
CN-119798108-A Preparation method of inner-ring profenofos and intermediate thereof in micro-channel 福州大学 2025-04-11 CN disclosed
CN-119798108-A Preparation method of inner-ring profenofos and intermediate thereof in micro-channel 福州大学 2025-04-11 CN disclosed
EP-3816150-B1 M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF CAC SHANGHAI INT TRADING CO LTD (CN) 2024-07-24 EP disclosed
CN-116178198-A Preparation method of cyflufenapyr 南通泰禾化工股份有限公司 2023-05-30 CN disclosed
CN-115974717-A Heptafluoroisopropyl-containing bisamide compound and intermediate compound thereof, and preparation method and application thereof 浙江宇龙药业有限公司 2023-04-18 CN disclosed
US-11540516-B2 M-diamide compound and preparation method therefor and use thereof CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) 2023-01-03 US disclosed
US-11540516-B2 M-diamide compound and preparation method therefor and use thereof CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) 2023-01-03 US disclosed
CN-113767907-B Pharmaceutical composition containing m-diamide compounds and application thereof 南通泰禾化工股份有限公司 2022-11-29 CN disclosed
CN-113767908-B Pharmaceutical composition containing m-diamide compound and application thereof 南通泰禾化工股份有限公司 2022-11-18 CN disclosed
EP-3816150-A1 M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF Cac Shanghai International Trading Co., Ltd. (CN) 2021-05-05 EP disclosed
US-20200178525-A1 M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREOF AND USE THEREOF CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) 2020-06-11 US disclosed
US-20200178525-A1 M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREOF AND USE THEREOF CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) 2020-06-11 US disclosed
CN-110810414-A Pharmaceutical composition containing m-diamide compound and application thereof 苏州佳辉化工有限公司 2020-02-21 CN disclosed
CN-110810409-A Pharmaceutical composition containing m-diamide compound and application thereof 上海泰禾国际贸易有限公司 2020-02-21 CN disclosed
CN-110810413-A Pharmaceutical composition containing m-diamide compound and application thereof 上海泰禾国际贸易有限公司 2020-02-21 CN disclosed
CN-110810410-A Pharmaceutical composition containing m-diamide compound and application thereof 上海泰禾国际贸易有限公司 2020-02-21 CN disclosed
CN-110810412-A Pharmaceutical composition containing m-diamide compound and application thereof 苏州佳辉化工有限公司 2020-02-21 CN disclosed
WO-2020030092-A1 PHARMACEUTICAL COMPOSITION CONTAINING M-DIAMIDE COMPOUND AND APPLICATION THEREOF 上海泰禾国际贸易有限公司 2020-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11540516-B2 M-diamide compound and preparation method therefor and use thereof DIMT1, DDT, MRM1 S1PR1 3653/4885LPAR1 3846/4885LPAR5 4127/4885
US-20200178525-A1 M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREOF AND USE THEREOF DDT, DIMT1, QDPR S1PR1 3752/4885LPAR1 3987/4885LPAR5 4397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.