SCHEMBL21705285

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21705232	0.96	HRH3 (0.40)	HRH3DRD3CYP2D6GAAKDM4E
	SCHEMBL21705921	0.92	HRH3 (0.41)	HRH3GAASLC29A1HPGDSMN1; SMN2
	SCHEMBL21705286	0.89	CYP2D6 (0.44)	HRH3DRD3CYP2D6GAAKDM4E
	SCHEMBL21783783	0.82	HRH3 (0.42)	HRH3DRD3CYP2D6GAAKDM4E
	SCHEMBL26426637	0.78	HRH3 (0.41)	HRH3DRD3CYP2D6GAAKDM4E
	SCHEMBL21705228	0.78	KMT2A (0.56)	CYP2D6KDM4EHPGDMEN1KMT2A
	SCHEMBL26426639	0.75	KDM4E (0.41)	HRH3DRD3CYP2D6GAAKDM4E
	SCHEMBL26426650	0.75	SLC29A1 (0.40)	HRH3DRD3CYP2D6GAAKDM4E
	SCHEMBL26354608	0.74	KMT2A (0.43)	HRH3DRD3CYP2D6GAAKDM4E
	SCHEMBL26586803	0.72	ESR1 (0.37)	CYP2D6SMN1; SMN2LMNACYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.