Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2170231 | 0.78 | LMNA (0.42) | TLR8 | |
| SCHEMBL3245965 | 0.73 | PIM1 (0.31) | DAGLA | |
| Hydrochloric Acid SCHEMBL2170595 | 0.72 | HRH1 (0.39) | TLR8HTR6CYP2A6 | |
| Hydrochloric Acid SCHEMBL1871819 | 0.67 | CYP2A6 (0.41) | CYP2A6 | |
| SCHEMBL17837530 | 0.66 | GLP1R (0.39) | GLP1R | |
| SCHEMBL27845919 | 0.66 | GLP1R (0.33) | GLP1R | |
| SCHEMBL27845932 | 0.66 | GLP1R (0.34) | GLP1R | |
| SCHEMBL569089 | 0.66 | GLP1R (0.34) | GLP1R | |
| SCHEMBL11585339 | 0.65 | LMNA (0.44) | GLP1RTLR8 | |
| SCHEMBL1348689 | 0.65 | ALDH1A1 (0.38) | GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346868-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010036632-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |