SCHEMBL11585339

SCHEMBL11585339

CS(=O)(=O)c1cc(Cl)nc(S(C)(=O)=O)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GLP1R P43220 10/20 0.38
BPTF Q12830 1/20 0.33
AURKA O14965 1/20 0.33
AURKB Q96GD4 1/20 0.33
NPSR1 Q6W5P4 3/20 0.33
TLR9 Q9NR96 3/20 0.33
SDHB P21912 3/20 0.33
STAT3 P40763 2/20 0.33
STAT1 P42224 2/20 0.33
RAB9A P51151 2/20 0.33
KMT2A Q03164 2/20 0.33
TP53 P04637 2/20 0.33
MAPK1 P28482 2/20 0.33
HTT P42858 2/20 0.33
HSD17B10 Q99714 2/20 0.33
MEN1 O00255 1/20 0.33
S1PR4 O95977 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL63292 0.87 LMNA (0.50) LMNASMN1; SMN2GLP1RBPTFAURKA
SCHEMBL9626200 0.84 LMNA (0.52) LMNASMN1; SMN2GLP1RBPTFNPSR1
SCHEMBL17837530 0.81 GLP1R (0.39) LMNASMN1; SMN2GLP1RALDH1A1
SCHEMBL6296316 0.79 LMNA (0.44) LMNASMN1; SMN2GLP1RAURKAAURKB
SCHEMBL8597269 0.78 LMNA (0.42) LMNASMN1; SMN2GLP1RBPTFAURKA
SCHEMBL11107779 0.78 LMNA (0.47) LMNASMN1; SMN2GLP1RBPTFAURKA
SCHEMBL13703901 0.78 LMNA (0.42) LMNASMN1; SMN2GLP1RBPTFAURKA
SCHEMBL7754155 0.77 LMNA (0.45) LMNASMN1; SMN2BPTFNPSR1TLR9
SCHEMBL8666206 0.76 SMN1; SMN2 (0.78) LMNASMN1; SMN2GLP1RNPSR1TLR9
SCHEMBL2614925 0.75 BPTF (0.55) LMNASMN1; SMN2BPTFAURKAAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4122079-A Reactive azo dyestuffs from diazotized sulfo-amino naphthalenes and diaminosulfobenzenes BAYER AKTIENGESELLSCHAFT (DE) 1978-10-24 US disclosed