SCHEMBL21705609

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21783771	0.89	KMT2A (0.39)	KMT2AMEN1HPGDATMSLC29A1
	SCHEMBL21705608	0.87	KMT2A (0.52)	KMT2AMEN1HPGDGLACYP3A4
	SCHEMBL21705615	0.86	HRH3 (0.48)	KMT2AMEN1HPGDSLC29A1GLA
	SCHEMBL21705605	0.85	ATM (0.54)	KMT2AHPGDATMALDH1A1CYP1A2
	SCHEMBL21705614	0.85	HPGD (0.41)	KMT2AMEN1HPGDATMSLC29A1
	SCHEMBL21705616	0.84	HRH3 (0.39)	KMT2AMEN1HPGDATMSLC29A1
	SCHEMBL21705720	0.78	KMT2A (0.52)	KMT2AMEN1HPGDALDH1A1CYP1A2
	SCHEMBL26426639	0.77	KDM4E (0.41)	KMT2AMEN1HPGDSLC29A1CYP3A4
	SCHEMBL21705754	0.76	KMT2A (0.50)	KMT2AMEN1HPGDSLC29A1GLA
	SCHEMBL21705213	0.75	KMT2A (0.52)	KMT2AMEN1HPGDGLACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.