SCHEMBL21705615

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21705608	0.88	KMT2A (0.52)	ALDH1A1KMT2AMEN1HTR4GLA
	SCHEMBL21783772	0.88	HRH3 (0.49)	HRH3SLC29A1ALDH1A1DRD3KMT2A
	SCHEMBL21705616	0.88	HRH3 (0.39)	HRH3SLC29A1ALDH1A1KMT2AMEN1
	SCHEMBL21705605	0.86	ATM (0.54)	ALDH1A1KMT2AHPGDLMNA
	SCHEMBL21705614	0.86	HPGD (0.41)	SLC29A1ALDH1A1KMT2AMEN1HTR4
	SCHEMBL21705609	0.86	KMT2A (0.39)	SLC29A1ALDH1A1KMT2AMEN1HTR4
	SCHEMBL26426639	0.81	KDM4E (0.41)	HRH3SLC29A1ALDH1A1DRD3KMT2A
	SCHEMBL21705754	0.77	KMT2A (0.50)	SLC29A1ALDH1A1KMT2AMEN1HTR4
	SCHEMBL24361311	0.77	KMT2A (0.50)	HRH3ALDH1A1DRD3KMT2AMEN1
	SCHEMBL26807538	0.77	ESR1 (0.43)	ALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.