SCHEMBL21705754

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21705213	0.99	KMT2A (0.52)	KMT2AHPGDMEN1GLACYP3A4
	SCHEMBL21783772	0.89	HRH3 (0.49)	KMT2AHPGDGLACYP3A4HTR4
	SCHEMBL21705199	0.88	ATM (0.52)	KMT2AHPGDCYP1A2ALDH1A1KDM4E
	SCHEMBL21783770	0.88	HPGD (0.41)	KMT2AHPGDMEN1GLACYP3A4
	SCHEMBL21783771	0.88	KMT2A (0.39)	KMT2AHPGDMEN1GLACYP3A4
	SCHEMBL21783773	0.87	HRH3 (0.39)	KMT2AHPGDMEN1GLACYP3A4
	SCHEMBL21705608	0.86	KMT2A (0.52)	KMT2AHPGDMEN1GLACYP3A4
	SCHEMBL24361311	0.85	KMT2A (0.50)	KMT2AHPGDMEN1GLACYP3A4
	SCHEMBL21705218	0.85	ALDH1A1 (0.46)	KMT2AHPGDMEN1GLACYP3A4
	SCHEMBL21705227	0.83	HTR4 (0.55)	KMT2AHPGDHTR4ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.