Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25753515 | 0.82 | TDP1 (0.50) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL22005509 | 0.82 | MAPK1 (0.54) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL19879688 | 0.79 | KMT2A (0.49) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL2725354 | 0.78 | RAB9A (0.54) | ALDH1A1TDP1KMT2ALMNARAB9A | |
| SCHEMBL24487505 | 0.77 | TDP1 (0.50) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL22644077 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL20255429 | 0.77 | HIF1A (0.56) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL27458875 | 0.76 | PRKCZ (0.44) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL29616312 | 0.75 | RAB9A (0.51) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL1244820 | 0.75 | TDP1 (0.57) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030924-A1 | THIAZOLEUREAS AS ANTICANCER AGENTS | ARTIOS PHARMA LIMITED (GB) | 2020-02-13 | — | — | WO | disclosed |