SCHEMBL21707884

SCHEMBL21707884

CC(C)c1ncc(Cc2ccc(O)cc2)[nH]c1=O

nearest known ligand 0.74

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 1/20 0.74
DAO P14920 4/20 0.40
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
MAPT P10636 2/20 0.36
KDM4A O75164 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
AOC3 Q16853 1/20 0.36
BRS3 P32247 3/20 0.35
GPR84 Q9NQS5 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20204667 0.88 CAPN1 (0.58) CAPN1DAOESR1ESR2MAPT
SCHEMBL21333942 0.85 CAPN1 (1.00) CAPN1DAOKDM4AAOC3BRS3
SCHEMBL21707855 0.84 CAPN1 (0.53) CAPN1DAOESR1ESR2MAPT
SCHEMBL20204670 0.81 CAPN1 (0.49) CAPN1ESR1ESR2GPR84
SCHEMBL20204597 0.74 CAPN1 (0.55) CAPN1DAOKDM4AAOC3BRS3
SCHEMBL21707883 0.73 CAPN1 (0.77) CAPN1DAOKDM4AAOC3BRS3
SCHEMBL21393119 0.71 CAPN1 (0.49) CAPN1DAO
SCHEMBL10567513 0.70 ESR1 (0.45) CAPN1ESR1ESR2AOC3BRS3
SCHEMBL12598583 0.70 AOC3 (0.69) ESR1ESR2AOC3ALDH1A1
SCHEMBL21707863 0.69 CAPN1 (0.71) CAPN1DAOKDM4AAOC3BRS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115651069-A Cyclochromo-threo-casein-valine-phenylpropanoid with hepatoma cytotoxicity and alpha-glucosidase inhibition activity and preparation method thereof 安徽农业大学 2023-01-31 CN claimed
WO-2025083273-A1 BINDING MOLECULES CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2025-04-24 WO disclosed
EP-4490205-A2 USES AND METHODS FOR IL-2, IL-13, AND IL-4 CYTOKINE BIFUNCTIONAL MOLECULES Medicenna Therapeutics, Inc. (CA) 2025-01-15 EP disclosed
EP-4444751-A1 IMMUNOTHERAPY FOR CANCER Cancer Research Technology Limited (GB) 2024-10-16 EP disclosed
CN-115716865-B Cyclic color-threo-tyr-valyl-leupeptin with hepatoma cytotoxicity and alpha-glucosidase inhibition activity and preparation method thereof 安徽农业大学 2024-04-30 CN disclosed
WO-2023170475-A2 USES AND METHODS FOR IL-2, IL-13, AND IL-4 CYTOKINE BIFUNCTIONAL MOLECULES MEDICENNA THERAPEUTICS, INC. (CA) 2023-09-14 WO disclosed
WO-2023105248-A1 IMMUNOTHERAPY FOR CANCER CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2023-06-15 WO disclosed
EP-4172198-A1 TAU BINDING MOLECULES Gen2 Neuroscience Limited (GB) 2023-05-03 EP disclosed
CN-115716865-A Cyclochro-threo-casein-valine-leucine peptide with hepatoma cytotoxicity and alpha-glucosidase inhibition activity and preparation method thereof 安徽农业大学 2023-02-28 CN disclosed
CN-115651069-A Cyclochromo-threo-casein-valine-phenylpropanoid with hepatoma cytotoxicity and alpha-glucosidase inhibition activity and preparation method thereof 安徽农业大学 2023-01-31 CN disclosed
US-11548916-B2 Anti-infective compound EBERHARD KARLS UNIVERSITAET TUEBINGEN (DE) 2023-01-10 US disclosed
EP-3990487-A1 TAU EPITOPE AND BINDING MOLECULES Gen2 Neuroscience Limited (GB) 2022-05-04 EP disclosed
CN-114262690-A Clonal strains of attenuated vaccinia virus and methods of use thereof 吉恩勒克斯公司 2022-04-01 CN disclosed
US-11124498-B2 Compositions and methods for modulating protease activity THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-09-21 US disclosed
US-20200048227-A1 COMPOSITIONS AND METHODS FOR MODULATING PROTEASE ACTIVITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11124498-B2 Compositions and methods for modulating protease activity RNASE1, ADAM8, CTRL CAPN1 81/4885DAO 2868/4885ESR1 1853/4885
US-20200048227-A1 COMPOSITIONS AND METHODS FOR MODULATING PROTEASE ACTIVITY RNASE1, ADAM8, CTRL CAPN1 81/4885DAO 2868/4885ESR1 1853/4885
US-11548916-B2 Anti-infective compound LCT, VIP, TLR5 CAPN1 3526/4885DAO 805/4885ESR1 4577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.