Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.52 |
| ▸ | RAB9A | P51151 | 13/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220899 | 0.83 | CASP3 (0.61) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2129269 | 0.80 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2130765 | 0.79 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1691257 | 0.76 | RAB9A (0.73) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1692241 | 0.75 | RAB9A (0.59) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL21708020 | 0.75 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL18807108 | 0.75 | RAB9A (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1984138 | 0.74 | RAB9A (0.84) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2088912 | 0.74 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL2086388 | 0.73 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | claimed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | claimed |
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | disclosed |
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | disclosed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | DOT1L, NSD1, KDM3A | NPC1 4209/4885RAB9A 3350/4885SMN1; SMN2 1685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.