Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 15/20 | 0.60 |
| ▸ | NPC1 | O15118 | 14/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18807109 | 0.84 | CASP3 (0.54) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL21708005 | 0.83 | NPC1 (0.52) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL18807108 | 0.82 | RAB9A (0.46) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL219665 | 0.79 | ALDH1A1 (0.55) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1661155 | 0.77 | CASP3 (0.73) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL3130863 | 0.76 | RAB9A (0.57) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL6391407 | 0.76 | CASP3 (1.00) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL2129269 | 0.75 | RAB9A (0.56) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31731985 | 0.75 | RAB9A (0.67) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL10978758 | 0.74 | RAB9A (0.62) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170324046-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME | HEESUNG MATERIAL LTD. (KR) | 2017-11-09 | — | — | US | disclosed |
| US-20170324046-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME | HEESUNG MATERIAL LTD. (KR) | 2017-11-09 | — | — | US | disclosed |
| EP-3214085-A2 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME | Heesung Material Ltd. (KR) | 2017-09-06 | — | — | EP | disclosed |
| US-9728730-B2 | Compound for organic optoelectric device and composition and organic optoelectric device and display device | SAMSUNG SDI CO., LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| US-9728730-B2 | Compound for organic optoelectric device and composition and organic optoelectric device and display device | SAMSUNG SDI CO., LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| EP-3165527-A1 | COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | Samsung Display Co., Ltd. (KR) | 2017-05-10 | — | — | EP | disclosed |
| US-20170125696-A1 | COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-05-04 | — | — | US | disclosed |
| US-20170125696-A1 | COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-05-04 | — | — | US | disclosed |
| US-20150303381-A1 | COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE AND COMPOSITION AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE | SAMSUNG SDI CO., LTD. (KR) | 2015-10-22 | — | — | US | disclosed |
| US-20150303381-A1 | COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE AND COMPOSITION AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE | SAMSUNG SDI CO., LTD. (KR) | 2015-10-22 | — | — | US | disclosed |
| WO-2007019346-A1 | BENZOTHIAZOLES AND THIAZOLOPYRIDINES AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | WO | disclosed |
| WO-2007019346-A1 | BENZOTHIAZOLES AND THIAZOLOPYRIDINES AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | WO | disclosed |
| WO-2007019344-A1 | IMIDAZO [2,1-B] THIAYOLE DERIVATIVES AS SIRTUIN MODULATING COMPOUNDS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | WO | disclosed |
| WO-2007019344-A1 | IMIDAZO [2,1-B] THIAYOLE DERIVATIVES AS SIRTUIN MODULATING COMPOUNDS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | WO | disclosed |
| US-20070037809-A1 | histone deacetylase inhibitors, used for treating preventing diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood disorders, inflammation, cancer, and/or hot flashes | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | US | disclosed |
| US-20070037809-A1 | histone deacetylase inhibitors, used for treating preventing diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood disorders, inflammation, cancer, and/or hot flashes | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | US | disclosed |
| US-20070037809-A1 | histone deacetylase inhibitors, used for treating preventing diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood disorders, inflammation, cancer, and/or hot flashes | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | US | disclosed |
| US-20070037827-A1 | Silent Information Regulators; aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting , increased mitochondrial activity, inflammation, cancer, and/or flushing; increased lifespan specially in mutant sir2 strains; imidazo[1,2-a]pyridine drivatives | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | US | disclosed |
| US-20070037827-A1 | Silent Information Regulators; aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting , increased mitochondrial activity, inflammation, cancer, and/or flushing; increased lifespan specially in mutant sir2 strains; imidazo[1,2-a]pyridine drivatives | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | US | disclosed |
| WO-2007019417-A1 | OXAZOLOPYRIDINE DERIVATIVES AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037827-A1 | Silent Information Regulators; aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting , increased mitochondrial activity, inflammation, cancer, and/or flushing; increased lifespan specially in mutant sir2 strains; imidazo[1,2-a]pyridine drivatives | SIRT2, SIRT1, SIRT3 | CASP3 977/4885SENP8 437/4885SENP7 637/4885 |
| US-20070037809-A1 | histone deacetylase inhibitors, used for treating preventing diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood disorders, inflammation, cancer, and/or hot flashes | SIRT1, SIRT3, SIRT2 | CASP3 674/4885SENP8 709/4885SENP7 874/4885 |
| US-20150303381-A1 | COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE AND COMPOSITION AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE | OR10J3, OXER1, OCIAD1 | CASP3 2376/4885SENP8 2812/4885SENP7 4339/4885 |
| US-20170125696-A1 | COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | VDAC1, VDAC2, MCOLN2 | CASP3 3386/4885SENP8 3981/4885SENP7 4028/4885 |
| US-20170324046-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME | CRY1, CRY2, PER2 | CASP3 2914/4885SENP8 1142/4885SENP7 2443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.