Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL661146 | 0.92 | S1PR1 (0.37) | HSD17B10MTNR1AMTNR1BS1PR1PIK3CD | |
| SCHEMBL662088 | 0.83 | S1PR1 (0.40) | HSD17B10MTNR1AMTNR1BS1PR1PIK3CD | |
| SCHEMBL21708174 | 0.80 | S1PR1 (0.37) | HSD17B10MTNR1AMTNR1BS1PR1PIK3CD | |
| SCHEMBL1666066 | 0.79 | MTNR1A (0.37) | MTNR1AMTNR1BS1PR1BRD4ACSS2 | |
| SCHEMBL30361134 | 0.78 | PPARG (0.39) | MTNR1AMTNR1BACSS2 | |
| SCHEMBL661457 | 0.78 | PPARG (0.39) | MTNR1AMTNR1BACSS2 | |
| SCHEMBL661964 | 0.77 | TP53 (0.39) | HSD17B10MTNR1AMTNR1BBRD4TP53 | |
| SCHEMBL4416615 | 0.75 | BRD4 (0.37) | MTNR1AMTNR1BBRD4TP53POLB | |
| SCHEMBL4406363 | 0.75 | BRD4 (0.37) | MTNR1AMTNR1BBRD4TP53 | |
| SCHEMBL4408527 | 0.75 | MTNR1A (0.37) | MTNR1AMTNR1BBRD4TP53ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3610890-A1 | METHODS AND COMPOSITIONS FOR TREATING SCHIZOPHRENIA | The Johns Hopkins University (US) | 2020-02-19 | — | — | EP | disclosed |