SCHEMBL2170837

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2168867	0.87	CXCR3 (0.42)	HSD11B1CXCR3ALDH1A1EPHX2
	SCHEMBL2168354	0.86	KMT2A (0.38)	HSD11B1GAAALDH1A1SMN1; SMN2
	SCHEMBL2169374	0.86	HTT (0.37)	HSD11B1TSHRALDH1A1
	SCHEMBL12013093	0.83	HSD11B1 (0.32)	HSD11B1
	SCHEMBL2180358	0.82	CMA1 (0.43)	GAAALDH1A1CYP2C19GSK3AGSK3B
	SCHEMBL2170272	0.82	KDM4E (0.38)	CHRM5ALDH1A1CYP3A4SMN1; SMN2
	SCHEMBL2168793	0.81	POLB (0.40)	ALDH1A1SMN1; SMN2
	SCHEMBL2169990	0.75	HSD11B1 (0.45)	HSD11B1TSHRALDH1A1HPGDCTSG
	SCHEMBL2169144	0.74	HSD11B1 (0.47)	HSD11B1CHRM2CHRM4CHRM5CXCR3
	SCHEMBL2169652	0.73	HSD11B1 (0.43)	HSD11B1CHRM2CHRM4CHRM5CXCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.