Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708658 | 0.89 | TAS1R3 (0.34) | PTGFRALDH1A1MC4RTAS1R3TAS1R1 | |
| SCHEMBL21708509 | 0.85 | NISCH (0.36) | PTGFRALDH1A1KDM4EL3MBTL1TAS1R3 | |
| SCHEMBL21708613 | 0.85 | TAS1R3 (0.33) | PTGFRTAS1R3TAS1R1 | |
| SCHEMBL21708770 | 0.84 | PTGFR (0.35) | PTGFRALDH1A1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL21708570 | 0.84 | NISCH (0.35) | PTGFRALDH1A1KDM4EL3MBTL1TAS1R3 | |
| SCHEMBL21708507 | 0.84 | PTGFR (0.33) | PTGFR | |
| SCHEMBL21708537 | 0.82 | PTGFR (0.33) | PTGFRMC4RL3MBTL1 | |
| SCHEMBL21708612 | 0.81 | TAS1R3 (0.32) | L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL21708785 | 0.81 | ROCK2 (0.32) | PTGFRALDH1A1L3MBTL1 | |
| SCHEMBL21708590 | 0.81 | L3MBTL1 (0.41) | TDP1KDM4ETSHRL3MBTL1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609870-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |