Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708746 | 0.90 | CNR2 (0.34) | CNR2KDM4EKMT2ACYP1A2CYP3A4 | |
| SCHEMBL21708548 | 0.85 | MEN1 (0.35) | KMT2AALDH1A1TDP1SLC6A4MAPK1 | |
| SCHEMBL21708707 | 0.85 | CCR1 (0.36) | CNR2KDM4EKMT2ACYP3A4ALDH1A1 | |
| SCHEMBL21708466 | 0.85 | F2R (0.36) | F2RPPARGKCNK3KCNK9 | |
| SCHEMBL21708512 | 0.84 | CCR1 (0.36) | KDM4EKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21708544 | 0.84 | POLB (0.38) | KMT2ATSHRPPARGPOLBHPGD | |
| SCHEMBL21708524 | 0.84 | CTSS (0.32) | F2REPHX2 | |
| SCHEMBL194920 | 0.83 | APP (0.41) | CNR2KDM4EKMT2ACYP1A2TSHR | |
| SCHEMBL28776287 | 0.83 | CTSK (0.37) | CNR2KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21708654 | 0.82 | MEN1 (0.38) | KDM4EKMT2ATSHRPPARGKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-3609870-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |