Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708758 | 0.86 | ROCK2 (0.45) | ROCK2ALDH1A1KCNQ2AOC3MAPK1 | |
| SCHEMBL21708677 | 0.84 | ROCK2 (0.49) | ROCK2KCNQ2AOC3CASRMAPK1 | |
| SCHEMBL21708787 | 0.81 | HPGD (0.39) | MEN1KMT2AALDH1A1CASRCYP1A2 | |
| SCHEMBL21656358 | 0.76 | MEN1 (0.44) | ROCK2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL21708777 | 0.73 | KMT2A (0.38) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL19612687 | 0.73 | MEN1 (0.49) | MEN1KMT2AALDH1A1NPSR1KCNQ2 | |
| SCHEMBL5820507 | 0.73 | MEN1 (0.60) | MEN1KMT2AALDH1A1NPSR1KCNQ2 | |
| SCHEMBL6985765 | 0.72 | MEN1 (0.63) | ROCK2MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL6983317 | 0.72 | MEN1 (0.63) | ROCK2MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL6976406 | 0.72 | MEN1 (0.63) | ROCK2MEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |