Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708512 | 0.93 | CCR1 (0.36) | CCR1CASP1L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL21708675 | 0.87 | CCR1 (0.37) | CCR1CASP1TAS1R3TAS1R1NPSR1 | |
| SCHEMBL21708716 | 0.81 | L3MBTL1 (0.36) | CASP1L3MBTL1CYSLTR2CYSLTR1PPARG | |
| SCHEMBL21708707 | 0.81 | CCR1 (0.36) | CCR1TAS1R3TAS1R1NPSR1MEN1 | |
| SCHEMBL21708518 | 0.81 | TAS1R3 (0.32) | L3MBTL1TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL21708548 | 0.81 | MEN1 (0.35) | CYSLTR2CYSLTR1NPSR1MEN1KMT2A | |
| SCHEMBL21708569 | 0.80 | KMT2A (0.33) | L3MBTL1KMT2A | |
| SCHEMBL21708544 | 0.80 | POLB (0.38) | L3MBTL1PPARGTAS1R3TAS1R1NPSR1 | |
| SCHEMBL21656588 | 0.79 | CCR1 (0.42) | CCR1CASP1ALDH1A1GLS | |
| SCHEMBL21632085 | 0.78 | CCR1 (0.48) | CCR1CYSLTR2CYSLTR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |