Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708531 | 0.90 | PTGFR (0.35) | CNR2KDM4EKMT2ACYP1A2CYP3A4 | |
| SCHEMBL21708766 | 0.84 | GABBR2 (0.33) | MAPK1SLC6A4POLB | |
| SCHEMBL21708713 | 0.84 | KCNK3 (0.37) | KCNK3KCNK9POLBPTGFR | |
| SCHEMBL21708646 | 0.83 | NISCH (0.37) | KDM4EKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21708643 | 0.83 | POLB (0.45) | KMT2ATSHRHPGDPPARGPOLB | |
| Hydrochloric Acid SCHEMBL21708730 | 0.81 | CTDSP1 (0.36) | KDM4EKMT2ATSHRPPARGPOLB | |
| SCHEMBL13703411 | 0.81 | CNR2 (0.43) | CNR2KDM4EKMT2ACYP1A2CYP3A4 | |
| SCHEMBL21708746 | 0.81 | CNR2 (0.34) | CNR2KDM4EKMT2ACYP1A2CYP3A4 | |
| SCHEMBL21656116 | 0.79 | POLB (0.40) | CNR2KDM4EKMT2AMAPK1HPGD | |
| SCHEMBL21632052 | 0.76 | GABBR2 (0.56) | CNR2KMT2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |