Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21708730 | 0.91 | CTDSP1 (0.36) | POLBHTTNPSR1L3MBTL1TSHR | |
| SCHEMBL21708590 | 0.89 | L3MBTL1 (0.41) | POLBHTTNPSR1L3MBTL1TSHR | |
| SCHEMBL21708713 | 0.89 | KCNK3 (0.37) | POLBHTTNPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL21708784 | 0.88 | GAA (0.37) | TAS1R3TAS1R1GAA | |
| SCHEMBL21708766 | 0.86 | GABBR2 (0.33) | POLBL3MBTL1 | |
| SCHEMBL21708646 | 0.85 | NISCH (0.37) | HTTNPSR1L3MBTL1TSHRKMT2A | |
| SCHEMBL21708747 | 0.84 | TAS1R3 (0.36) | POLBHTTNPSR1L3MBTL1TSHR | |
| SCHEMBL21708697 | 0.83 | CNR2 (0.35) | POLBTSHRKMT2AHPGDPPARG | |
| SCHEMBL21708709 | 0.83 | PTGFR (0.35) | HTTL3MBTL1TSHRKMT2AMEN1 | |
| SCHEMBL21708695 | 0.80 | MEN1 (0.38) | POLBHTTNPSR1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |