Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708509 | 0.89 | NISCH (0.36) | NISCHCASP1TAS1R3TAS1R1MEN1 | |
| Hydrochloric Acid SCHEMBL21708570 | 0.88 | NISCH (0.35) | NISCHCASP1TAS1R3TAS1R1MEN1 | |
| SCHEMBL21708716 | 0.87 | L3MBTL1 (0.36) | NISCHCASP1TAS1R3TAS1R1MEN1 | |
| SCHEMBL21708792 | 0.86 | TAS1R3 (0.33) | TAS1R3TAS1R1LMNAMEN1KMT2A | |
| SCHEMBL21708766 | 0.86 | GABBR2 (0.33) | GABBR2GABBR1ROCK2ALDH1A1L3MBTL1 | |
| SCHEMBL21708643 | 0.85 | POLB (0.45) | TAS1R3TAS1R1MEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL21708730 | 0.83 | CTDSP1 (0.36) | MEN1RAB9AKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21708697 | 0.83 | CNR2 (0.35) | MAPTKMT2AHPGDKDM4ECYP1A2 | |
| SCHEMBL21708602 | 0.82 | SMN1; SMN2 (0.33) | MEN1KMT2AHPGDALDH1A1L3MBTL1 | |
| SCHEMBL21708717 | 0.82 | CASP1 (0.36) | CASP1TAS1R3TAS1R1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |