Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 3/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708593 | 0.86 | CES2 (0.34) | CES2CES1 | |
| SCHEMBL21708727 | 0.84 | PTGFR (0.30) | PTGFR | |
| SCHEMBL21708537 | 0.84 | PTGFR (0.33) | PTGFR | |
| SCHEMBL21708517 | 0.83 | PTGFR (0.35) | PTGFR | |
| SCHEMBL21708658 | 0.81 | TAS1R3 (0.34) | CES2CES1PTGFR | |
| SCHEMBL21708737 | 0.81 | CES2 (0.33) | CES2CES1 | |
| SCHEMBL21656226 | 0.80 | CES2 (0.36) | CES2CES1PTGFRTRPM8 | |
| SCHEMBL21708464 | 0.77 | PTGFR (0.35) | PTGFR | |
| SCHEMBL21708613 | 0.77 | TAS1R3 (0.33) | CES2CES1PTGFR | |
| SCHEMBL21632237 | 0.77 | CES2 (0.42) | CES2CES1PTGFRTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |